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Brain Waste Disposal May Resolve Parkinson’s

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Parkinson’s disease, a progressive neurological disorder that damages dopamine-producing neurons in the brain, affects more than 10 million people worldwide. It causes the loss of nerve cells that control movement, resulting in tremors, stiffness, slow movement and balance issues. Researchers attribute nerve cell loss to a buildup of misfolded alpha-synuclein protein due to a faulty waste disposal system in the brain.

Researchers from Swinburne University of Technology, in Australia, have developed a compound that removes Parkinson’s-associated proteins from mice by enhancing the brain’s waste disposal system, resulting in balance and mobility improvements. In April, their findings were presented at the Oxford Glymphatic & Brain Clearance Symposium, in the UK. The researchers hope to secure approval for early-stage human testing within a year.

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